Drug Index

Carbachol

 
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Mechanism :

Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known.


Indication :

• Intraocular use for obtaining miosis during surgery

• Reduction of intraocular pressure elevation in the first 24 hours after cataract surgery


Contraindications :

Should not be used in those persons showing hypersensitivity to any of the components of this preparation.


Dosing :

Available as intraocular solution, USP 0.01%

Glaucoma:

1-2 drops in the conjunctival sac thrice daily.

Miotic During ocular surgery:

Max: 0.5 ml should be gently instilled into the anterior chamber for the production of satisfactory miosis.


Adverse Effect :

Should not be used in those persons showing hypersensitivity to any of the components of this preparation.

Corneal clouding, persistent bullous keratopathy, retinal detachment, postoperative iritis. With systemic use can lead to flushing, sweating, epigastric distress, abdominal cramps, tightness in urinary bladder, headache.

07/18/2019 09:53:35 Carbachol
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