Drug Index

Copper

Mechanism :

Copper is an essential trace element. It is a cofactor for various enzymes. It is required for the formation of transferrin and the maintenance of erythropoiesis.  There by maintain normal rates of red and white cell formation that help prevent development of deficiency symptomes.


Indication :

  • Dietary Supplementation

Contraindications :

  1. Caution in:

- Wilson disease

- Hepatic impairment

- Premature infants



Dosing :

Available as capsules and tablets of 5 mg and as solution (iv) of 0.4 mg/ml (10 ml).
Dose for parenteral nutrition: 20 mcg/kg/day IV.
Recommended Dietary Allowance:
0-6 months old: 200 mcg per day.
7-12 months old: 220 mcg per day.
1-3 years old: 340 mcg per day.
3-8 years old: 440 mcg per day.
8-13 years old: 700 mcg per day.
13-18 years old: 890 mcg/day.

Adverse Effect :

  1.  Nausea, vomiting
  2.  Hepatic dysfunction



Interaction :

Alternate use recommended:

  1.  Baloxavir marboxil: Copper decreases the of this drug by binding to it in the GIT.

Close monitoring required:

  1.  Tetracyclines eg: Omadacyline, Sarecycline: Copper decreases the level of these drugs by inhibiting its absorption.
  2.  Penicillamine: Copper is an antagonist and hence decreases its action.

Minor: The following drugs decrease the level of copper by inhibiting its GI absorption.

  1.  Ascorbic acid
  2.  Trientine


12/12/2023 16:33:45 Copper
Disclaimer: The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0