Drug Index

Doripenem

 
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Indication :

• Complicated intra-abdominal infections

• Complicated UTI

• Bronchopulmonary infections


Dosing :

Safety and efficacy not established in children <18 years.

Neonates >32 weeks gestation: 10-15 mg/kg/dose IV in 8-12 hourly doses for at least 2 weeks.

>1 month: 20 mg/kg/dose IV divided in 8 hourly doses for at least 2 weeks. Max: 500 mg/dose.


Adverse Effect :

Anaphylaxis, seizures, Clostridium difficile-associated diarrhea, anemia, headache, nausea, diarrhea, rash, phlebitis, elevated hepatic enzymes, leukopenia, neutropenia, thrombo- ytopenia, Toxic epidermal necrolysis, Stevens-Johnson syndrome.

07/18/2019 09:18:25 Doripenem
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