Factor VIIa
Indication :
- Hemophilia A or B with inhibitors
- Congenital factor VII deficiency
Dosing :
Bleeding episodes in Hemophilia A or B:
90 mcg/kg IV every 2 hours till bleeding stops. Continue for 3-6 hours after bleeding stops. Post-surgical give for 5 days and then every 4 hours till bleeding stops.
Congenital Factor VII deficiency:
15-30 mcg/kg IV every 4-6 hours till bleeding stops.
Adverse Effect :
Headache, hypertension, flushing, fever, chills, vomiting, nausea, lethargy, or manifestations of allergic reactions.
Hepatic Dose :
No dosage adjustments are recommended.