Guaifenesin
Synonym :
Guaiphenesin
Mechanism :
It is an expectorant used in cough syrups to reduce the viscosity of tenacious sputum.
Indication :
- Expectorant for coughing out phlegm, for thinning bronchial secretions.
Contraindications :
Hypersensitivity to drug or component.
Dosing :
In children, 6 months-2 years:
25-50 mg every 4 hours; Max: 300 mg/day.
2-6 years:
50-100 mg orally every 4 hours. Max: 600 mg/day.
6-12 years:
100-200 mg every 4 hours. Max: 1.2 g/day.
>12 years:
100-400 mg orally every 4 hours; Max: 2.4 g/day.
Adverse Effect :
Rash, vomiting, nausea, nephrolithiasis.
Interaction :
None.
Hepatic Dose :
No dosage adjustment is needed.