Luliconazole
Mechanism :
Azole antifungal that appears to inhibit ergosterol synthesis by inhibiting the enzyme lanosterol demethylase, resulting in decreased amounts of ergosterol and a corresponding accumulation of lanosterol.
Indication :
- Topical treatment of interdigital tinea pedis, tinea cruris, and tinea corporis caused by Trichophyton rubrum and Epidermophyton floccosum.
Contraindications :
No contraindications.
Dosing :
Topical
Tinea pedis or tinea cruris:
Children ≥12 years and Adolescents:
Apply to affected area and ~1 inch of immediate surrounding areas once daily for 2 weeks.
Topical
Tinea corporis:
Children ≥2 years and Adolescents:
Apply to affected area and ~1 inch of immediate surrounding areas once daily for 1 week.
Adverse Effect :
Application site reaction, cellulitis, contact dermatitis.
Interaction :
Cilostazol: CYP2C19 Inhibitors may increase the serum concentration of Cilostazol.
Hepatic Dose :
No dose adjustments are recommended.