Drug Index

Nandrolone

 
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Mechanism :

It is an anabolic steroid used in treatment of hypoplastic anemia and suboptimal growth in children.


Indication :

• Refractory deficient red cell production anemias

• Breast carcinoma

• Hereditary angioedema

• Antithrombin III deficiency

• Fibrinogen excess

• Growth failure

• Turner’s syndrome


Contraindications :

Pregnancy, Hypersensitivity, Prostatic cancer, Breast cancer, Breast cancer with high calcium, Kidney disease.


Dosing :

2 to 13 years of age: 25 to 50 mg PO every 3 to 4 weeks.


Adverse Effect :

Edema, cholestatic jaundice, gynaecomastia, precocious puberty and on long term use may cause short stature.


Interaction :

Warfarin: Nandrolone may increase the serum concentration and anticoagulant effect of warfarin. Monitor for changes in prothrombin time and therapeutic effects of warfarin if nandrolone is initiated, discontinued or dose changed.


07/13/2019 01:12:53 Nandrolone
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