Drug Index

Penciclovir

 
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Mechanism :

Penciclovir triphosphate inhibits HSV polymerase competitively with deoxyguanosine triphosphate, thereby inhibiting herpes viral DNA synthesis.


Indication :

• Topical treatment of recurrent herpes labialis (cold sores)


Contraindications :

Hypersensitivity to the penciclovir or any component of the formulation.


Dosing :

≥12 years: Apply cream (1%) at the first appearance of cold sore every 2 hours during waking hours for 4 days.


Adverse Effect :

Erythema, headache, application site reaction, altered sense of smell, erythematous rash, local anaesthesia, localized edema, oropharyngeal edema, pain, paresthesia, pruritus.


Interaction :

Talimogene Laherparepvec: Antiherpetic Antivirals may diminish the therapeutic effect of Talimogene Laherparepvec.


07/14/2019 06:47:29 Penciclovir
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