Drug Index

Potassium Citrate/Citric acid

Mechanism :

Potassium citrate is absorbed and metabolized to potassium bicarbonate and this acts as a systemic alkalizer.

Indication :

  • Acidosis
  • Systemic alkalizer

Contraindications :

Hypersensitivity to any ingredient of the formulation, severe renal insufficiency with oliguria or azotemia; potassium-restricted diet; untreated Addison disease; adynamia episodica hereditaria; acute dehydration; heat cramps; anuria; severe myocardial damage; hyperkalemia.

Dosing :

5 to 15 mL (1100 mg/334 mg/5 ml) PO 4 times daily diluted in 1 glass of water.

Adverse Effect :

Hyperkalemia, alkalosis

Interaction :

Aluminium Hydroxide: Citric Acid Derivatives may increase the absorption of Aluminium Hydroxide.
Amphetamines: Alkalinizing Agents may decrease the excretion of Amphetamines.
Potassium-Sparing Diuretics: Potassium Salts may enhance the hyperkalemic effect of Potassium-Sparing Diuretics.
Anticholinergic Agents: May enhance the ulcerogenic effect of Potassium Citrate.

Hepatic Dose :

No dosage adjustments are recommended.
03/23/2024 05:57:49 Potassium Citrate/Citric acid
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