Potassium Citrate/Citric acid
Mechanism :
Potassium citrate is absorbed and metabolized to potassium bicarbonate and this acts as a systemic alkalizer.
Indication :
- Acidosis
- Systemic alkalizer
Contraindications :
Hypersensitivity to any ingredient of the formulation, severe renal insufficiency with oliguria or azotemia; potassium-restricted diet; untreated Addison disease; adynamia episodica hereditaria; acute dehydration; heat cramps; anuria; severe myocardial damage; hyperkalemia.
Dosing :
5 to 15 mL (1100 mg/334 mg/5 ml) PO 4 times daily diluted in 1 glass of water.
Adverse Effect :
Hyperkalemia, alkalosis
Interaction :
Aluminium Hydroxide: Citric Acid Derivatives may increase the absorption of Aluminium Hydroxide.
Amphetamines: Alkalinizing Agents may decrease the excretion of Amphetamines.
Potassium-Sparing Diuretics: Potassium Salts may enhance the hyperkalemic effect of Potassium-Sparing Diuretics.
Anticholinergic Agents: May enhance the ulcerogenic effect of Potassium Citrate.
Hepatic Dose :
No dosage adjustments are recommended.