Drug Index

Potassium Citrate/Citric acid

 
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Mechanism :

Potassium citrate is absorbed and metabolized to potassium bicarbonate and this acts as a systemic alkalizer.


Indication :

• Acidosis

• Systemic alkalizer


Contraindications :

Hypersensitivity to any ingredient of the formulation, severe renal insufficiency with oliguria or azotemia; potassium-restricted diet; untreated Addison disease; adynamia episodica hereditaria; acute dehydration; heat cramps; anuria; severe myocardial damage; hyperkalemia.


Dosing :

5 to 15 mL (1100 mg/334 mg/5 ml) PO 4 times daily diluted in 1 glass of water.


Adverse Effect :

Hyperkalemia, alkalosis


Interaction :

Aluminium Hydroxide: Citric Acid Derivatives may increase the absorption of Aluminium Hydroxide.
Amphetamines: Alkalinizing Agents may decrease the excretion of Amphetamines.
Potassium-Sparing Diuretics: Potassium Salts may enhance the hyperkalemic effect of Potassium-Sparing Diuretics.
Anticholinergic Agents: May enhance the ulcerogenic effect of Potassium Citrate.


07/15/2019 06:39:12 Potassium Citrate/Citric acid
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