Drug Index

Sacrosidase

 
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Mechanism :

Sacrosidase is a naturally-occurring gastrointestinal enzyme derived from baker's yeast (Saccharomyces cerevisiae) which breaks down the disaccharide sucrose to its monosaccharide components.


Indication :

• Oral replacement therapy in sucrase deficiency, as seen in congenital sucrase isomaltase deficiency (CSID)


Contraindications :

Hypersensitivity to yeast, yeast products, glycerine (glycerol), or papain.


Dosing :

Infants ≥5 months and Children ≤15 kg: Oral: 8,500 units (1 mL) per meal or snack.

Children >15 kg and Adolescents: Oral: 17,000 units (2 mL) per meal or snack.


Adverse Effect :

Headache, insomnia, nervousness, dehydration, abdominal pain, constipation, diarrhea, nausea, vomiting.


Interaction :

No known significant interactions.


07/15/2019 06:28:34 Sacrosidase
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