Drug Index

Tigecycline

 
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Mechanism :

Tigecycline is an antibiotic. It works by killing sensitive bacteria.


Indication :

• Safety and efficacy not established in children.

• Multidrug resistant gram-negative bacterial infections.


Contraindications :

Hypersensitivity.


Dosing :

8-11 years: 1.2 mg/kg IV every 12 hours. Max: 50 mg/12 hours.

12-17 years: 50 mg IV every 12 hours.


Adverse Effect :

Dizziness, fever or chills, headache, lower back or side pain, warmth, or burning in the fingers, toes, and legs; painful or difficult urination, problems with vision or hearing.

Rare: Abdominal pain, angioedema, diarrhea, fat in the stool, irregular heartbeat.


Interaction :

Blood Thinners: Some products that may interact with this drug include: "blood thinners" (e.g., warfarin), live bacterial vaccines, retinoid medications taken by mouth (such as acitretin, isotretinoin).
Rifamycins: Although most antibiotics probably do not affect hormonal birth control such as pills, patch, or ring, some antibiotics may decrease their effectiveness. This could cause pregnancy. Examples include rifamycins such as rifampin or rifabutin.


07/15/2019 05:55:04 Tigecycline
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