Pyrethrins and pyrethroids

They are extracted from chrysanthemum plant and used as insect repellants and pesticides. They are available as sprays, dusts, powders and mats
Route :
Ingestion, inhalation, skin contact
Fatal Dose :
1gm/kg body weight
Fatal Period :
2 to 5 days
Mechanism of action :
They prolong the inactivation of sodium channel by binding it in the inactive state
Clinical Picture :
•Skin contact causes dermatitis and blistering
•Paraesthesias, nausea, vomiting, and diarrhea
•Inhalation causes rhinorrhea, sore throat, wheezing and dyspnoea
•Fasciculations, hyperthermia, altered mental status
•Convulsions and coma

Treatment :
•Gastric lavage with activated charcoal
•Oils and fats to be avoided
•Atropine and oximes are contraindicated
•Skin should be washed
08/10/2024 22:52:23 Pyrethrins and pyrethroids
Disclaimer: The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0