Menu
Disease
A-Z
Health Topics
Alternative Medicine
Developmental Pediatrics
General Pediatrics
Genetics
Immunodeficiencies
Infectious Diseases
Laboratory Medicine
Neonatology
Nutrition
Pediatric Cardiology
View all Topics
Featured Articles
Urticaria (hives) and angioedema
Circumcision
Anal fissure
Skin allergies
Hypospadias
Anaphylaxis
Kids Corner
Health and Knowledge with fun.
Drugs &
Calculators
Medical Calculators
Drug Calculators
Growth Calculators
Renal Calculators
View all Calcualtors
Drug Index
ACE inhibitor
Alkylating agents
Allergies
View all Drugs
Poisoning Center
Aluminum phosphide
Anti-histaminics
Antidepressants
View all Drugs
Medical Eqipments
Monitors
Pumps
Incubators
View all Equipments
Diagnostic Aid
Get your diffrential
diagnosis.
Consult
& Posts
Ask a Doctor
Diagnostic Dilemma
Question of the Week
Pediatric Blogs
Spot Diagnosis
Grand Rounds
Pedi Poll
Pediatric
Journal
Current Issue
All Issues
Advance Access
About the Journal
Submit Article
Books
& Apps
Book Store
Pediatric Oncall
Medical Calculators
Vaccine Reminder
Pediatric Oncall Journal
Drug Center
Parenting
CME &
Videos
Upcoming Conferences
Conference Abstracts
MCQs
Videos
Vaccine
Reminder
Sign In
Diseases and Conditions
›
Genetics
›
Tuberous Sclerosis
Tuberous Sclerosis
Ira Shah
More..
Tuberous Sclerosis - Introduction
Tuberous sclerosis is a complex genetic disorder (a disease that occurs due to some defect in the genes) that is characterized by skin lesions, nervous system affectation and renal involvement primarily. The name is derived from tuber - like growths on the brain that become hard. These tubers are seen as white areas on a CT Scan of the brain. These abnormal growths can affect any organ of the body (even the eyes, kidneys, heart and the lungs).
EVERY INDIVIDUAL WITH TUBEROUS SCLEROSIS IS AFFECTED DIFFERENTLY. SOME INDIVIDUALS ARE TOTALLY UNAFFECTED WHEREAS SOME PEOPLE ARE MORE SEVERELY AFFECTED.
How Common Is Tuberous Sclerosis?
Out of every 6000 newborns, one may have tuberous sclerosis. More than 1 million people around the world are known to have tuberous sclerosis. These may still be many undiagnosed cases and mild forms of the disease.
Why Does Tuberous Sclerosis Occur?
Tuberous sclerosis is a genetic disorder (due to errors in the genes). Children have a 50% chance of inheriting tuberous sclerosis if one of the parents have this condition. However 2/3rd of the cases are due to spontaneous genetic errors, the cause of which is still a mystery.
Why Does Tuberous Sclerosis Affect So Many Body Organs?
In tuberous sclerosis, there is a growth of normal body tissue in a disorganized way (hamartomas). They interfere with the functioning of the organ in which they are growing. When the person becomes an adult, the growth of the organ and the hamartoma stops. As a result, most patients have a normal life span. However, there may be occasional serious problems (kidney, lung or brain tumours) that need to be dealt with later in life.
References
Ira Shah
Tuberous Sclerosis
Tuberous Sclerosis
02/27/2001
02/27/2001
×
Contributor Information and Disclosures
Ira Shah
Consultant Pediatrician, B.J.Wadia Hospital for Children, Mumbai, India
First Created:
02/27/2001
×
References
National Tuberous Sclerosis Association (Tuberous Sclerosis Alliance)
The Tuberous Sclerosis Association online
Tuberous Sclerosis - Presentation
>>
Related
More from Tuberous Sclerosis
Tuberous Sclerosis - Presentation
Diagnostic Criteria
Antenatal Diagnosis
Tuberous Sclerosis - Patient Education
Tuberous Sclerosis - Diagnosis
Tuberous Sclerosis - Management
Tuberous Sclerosis - Prognosis
More from Genetics
Aarskog Syndrome
Abetalipoproteinemia
Achondroplasia
Aplasia Cutis Congenita
Down's Syndrome
View all from Genetics
Ask a Doctor
Book Store
Infection in Children - Part 2
Order Now
Recommended for you
Appendicitis
Amniotic Bands
Mudra (Body Postures)
Spot Diagnosis
Skin Hemangiomas with Limb Hypertrophy
Generalized Dilated Superficial Veins and Telangiectasia in a Newborn Infant
Nail Changes in a Child with Acute Lymphoblastic Leukemia
View All
Grand Round
Dilemma
A Queer Case of Thrombocytopenia in a Child
Answer
Recurrent ketotic hypoglycemia
Congenital hydrocephalus: communicating or obstructive_?
Recurrent tuberculosis
This girl presented with jaundice, skin lesions and anemia of 15 days duration. She was diagnosed to...
Answer
Is it wilson`s disease_?
Neurocysticercosis or tuberculoma
Hypoplastic marrow
Pediatric Oncall Journal
Original Article
Cord blood Thyroid Stimulating Hormone Level - and the influence of perinatal and other factors on it
Case Reports
Images In Clinical Practice
Generalized Dilated Superficial Veins and Telangiectasia in a Newborn Infant
Disclaimer: The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.
X
Sign In
Disease A-Z
Health Topics
Alternative Medicine
Developmental Pediatrics
General Pediatrics
Genetics
Immunodeficiencies
Infectious Diseases
Laboratory Medicine
Neonatology
Nutrition
Pediatric Cardiology
View all topics
Featured Articles
Urticaria (hives) and angioedema
Circumcision
Anal fissure
Skin allergies
Hypospadias
Anaphylaxis
Kids Corner
Drugs & Calculators
Medical Calculators
Drug Calculators
Growth Calculators
Renal Calculators
View all Calculators
Drug Index
ACE inhibitor
Alkylating agents
Allergies
View all Drugs
Poisoning Center
Aluminum phosphide
Anti-histaminics
Antidepressants
View all Drugs
Medical Eqipments
Monitors
Pumps
Incubators
View all Eqipments
Diagnostic Aid
Consult & Posts
Ask a Doctor
Diagnostic Dilemma
Question of the Week
Pediatric Blogs
Spot Diagnosis
Grand Rounds
Pedi Poll
Pediatric Oncall Journal
Current Issue
All Issues
Advance Access
About the Journal
Submit Article
Books & Apps
Book Store
Pediatric Oncall
Medical Calculators
Vaccine Reminder
Pediatric Oncall Journal
Drug Center
Parenting
CME & Videos
Upcoming Conferences
Conference Abstracts
MCQs
Videos
Vaccine Reminder
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0