Inflammatory Bowel Disease (IBD)

Dr Sharad Shah
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Inflammatory Bowel Disease (IBD) - Presentation
Apart from diarrhea and blood in stools, other manifestations are:
Ulcerative colitis: The extra-intestinal manifestations are the same as Crohn's disease but in some ways they vary. The eyes, mouth, skin, joints are involved more frequently in UC. Liver disease (Primary sclerosing cholangitis) is seen in 3% of all patients.
The other rare associations are pericarditis with or without effusion and amyloidosis.

Crohn's disease: Patient may have obstruction, fistula formation (they can develop entero-enteral fistula, enterovesical fistula enterovaginal fistula and enterocutaneous fistula) and intra-abdominal abscess. The extra-intestinal manifestation will be
- Colitis related
- Consequence of small bowel pathophysiology
- Miscellaneous
- Colitis Related: Peripheral arthropathy, erythema nodosum, episcleritis, fatty liver, aphthous ulcers (10%), pyoderma gangrenosum (1-2%). Clubbing, pelvis osteomyelitis and osteomalacia.
- Consequences of small bowel pathophysiology: Malabsorption, gall stone formation (15-30%). Steatorrhea, diarrhea, bacterial overgrowth may lead to surgical resection. Pancreatitis.
- Miscellaneous : Amyloidosis, thrombo-embolic phenomenon, hepato biliary disease - primary sclerosing cholangitis.

1/4th of patients present with CD before 20 years of age. Arthritis and arthralgia are seen in about 15% of children. There may also be growth failure, anemia and delayed puberty.


Inflammatory Bowel Disease (IBD) Inflammatory Bowel Disease (IBD) 02/23/2001
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