Tracheo-Oesophageal Fistula

Sunita Goel
Tracheo-Oesophageal Fistula - History
Its incidence is about 1/4000. It was first described 1670. Surgical correction was started only in 1920s. The first survivors were reported in 1939. Extrapleural approach was reported in 1941.

- It occurs between the 21st and 34th days of fetal development.
- From the Ventral diverticulum of foregut, masses of endodermal cells divide foregut into trachea and oesophagus. It begins at carina and its imperfect division results in TOF.
- Explanation of Esophageal Atresia is less clear.
- Growth of trachea in caudal direction is so rapid that dorsal wall of oesophagus becomes incorporated into trachea.
- Other etiologies: "Vascular deficiency" Genetic basis.

Tracheo-Oesophageal Fistula Tracheo-Oesophageal Fistula 02/23/2001
Tracheo-Oesophageal Fistula - Classification >>
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