Drug Index

Anidulafungin

 
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Indication :

• Candidemia


Dosing :

Safety and efficacy not established in children. 3 mg/sqm IV as loading dose followed by 1.5 mg/sqm/dose IV once a day for 14 days after last culture report is positive.


Adverse Effect :

Diarrhea, hypokalemia, elevated transaminases, urticaria, flushing, hypotension.


Renal Dose :

Dose in Renal Impairment GFR (mL/min)
20-50Dose as in normal renal function
10-20Dose as in normal renal function
<10Dose as in normal renal function

Dose in Patients undergoing Renal Replacement Therapies
CAPDNot dialysed. Dose as in normal renal function
HDNot dialysed. Dose as in normal renal function
HDF/High fluxUnlikely to be dialysed. Dose as in normal renal function
CAV/VVHDUnlikely to be dialysed. Dose as in normal renal function

Hepatic Dose :

No dosage adjustments are recommended. Consider risk: benefit ratio of continuing treatment if liver functions deteriorate during anidulafungin treatment.
04/04/2020 06:02:07 Anidulafungin
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