Drug Index

Carteolol Ophthalmic Solution

 
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Mechanism :

Carteolol HCl is a nonselective beta-adrenergic blocking agent with associated intrinsic sympathomimetic activity and without significant membrane-stabilizing activity. Carteolol reduces normal and elevated intraocular pressure (IOP) whether or not accompanied by glaucoma. The exact mechanism of the ocular hypotensive effect of beta-blockers has not been demonstrated.


Indication :

• Chronic open-angle glaucoma

• Intraocular hypertension


Contraindications :

Contraindicated in those individuals with bronchial asthma or with a history of bronchial asthma, or severe chronic obstructive pulmonary disease; sinus bradycardia; second- and third-degree atrioventricular block; overt cardiac failure; cardiogenic shock; or hypersensitivity to any component of this product.


Dosing :

One drop of 1% solution, in the affected eye(s) twice a day.


Adverse Effect :

Transient eye irritation, burning, tearing, conjunctival hyperemia and edema, bradycardia, hypotension, cardiac arrhythmia, headache, dizziness, insomnia, sinusitis, taste perversion.


Interaction :

Beta-adrenergic blocking agent: Should be used with caution in patients who are receiving a beta-adrenergic blocking agent orally because of the potential for additive effects on systemic beta-blockade.
Close observation of the patient is recommended when a beta-blocker is administered to patients receiving catecholamine-depleting drugs such as reserpine, because of possible additive effects and the production of hypotension and/or marked bradycardia, which may produce vertigo, syncope, or postural hypotension.


07/14/2019 20:18:21 Carteolol Ophthalmic Solution
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