Drug Index

Indication :

  • It is an integrase inhibitor used in the treatment of HIV.

Dosing :

<30 kg:
Safety not established.
30 kg-40 kg:
35 mg orally once a day.
>40 kg:
50 mg orally once a day.

Adverse Effect :

Hypercholesterolemia, hypertriglyceridemia and elevated liver transaminases, lipase, bilirubin, creatine kinase, blood sugar. Can cause arthralgia, myalgia.

Interaction :

Efavirenz, Fosamprenavir/Ritonavir, Tipranavir/Ritonavir, Rifampin: Give twice a day when using along with efavirenz, fosamprenavir/ritonavir, tipranavir/ritonavir, rifampin.

Hepatic Dose :

Mild to moderate hepatic impairment: No dose adjustment required.
Severe hepatic impairment: Use is contraindicated.
09/22/2020 11:34:08 Dolutegravir
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