Drug Index

Elamipretide

 
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Mechanism :

Mitochondria-targeting peptide; free radical scavenger and antioxidant that penetrates the cellular and outer mitochondrial membranes, and targets cardiolipin, which is found exclusively in the inner mitochondrial membrane.


Indication :

• Pending FDA approval

• Mitochondrial Myopathies

• Optic Neuropathy

• Leber’s Hereditary Optic Neuropathy


Dosing :

Only for use in children >16 years of age.

0.01-0.25 mg/kg/h IV infusion over 2 hours for 5 days.


Adverse Effect :

Headache, dizziness, abdominal pain, flatulence.

07/17/2019 21:22:51 Elamipretide
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