Galsulfase
Mechanism :
Galsulfase is a recombinant form of N-acetylgalactosamine 4-sulfatase, produced in Chinese hamster cells.
Indication :
- Mucopolysaccharidosis VI (Maroteaux-Lamy syndrome)
Contraindications :
No contraindications.
Dosing :
IV:
1 mg/kg once weekly.
Adverse Effect :
Chest pain, hypertension, pain, chills, absent reflexes, skin rash, pruritus, urticarial, abdominal pain, angioedema, arthralgia, corneal opacity, conjunctivitis, otalgia, dyspnea, antibody formations, infusion related reactions.
Interaction :
No known significant interactions.
Hepatic Dose :
No dosage adjustments are needed.