Drug Index

Halobetasol Propionate

Mechanism :

Inhibits multiple inflammatory cytokines; produces multiple glucocorticoid and mineralocorticoid effects.

Indication :

  • Inflammatory, pruritic & steroid-responsive dermatoses
  • Adjunctive treatment in nodular prurigo
  • Chronic discoid lupus erythematosus
  • Familial benign pemphigus
  • Dyshidrosis
  • Mycosis fungoides
  • Alopecia areata
  • Psoriasis
  • Seborrheic dermatitis

Contraindications :

Hypersensitivity to drug/class/component.

Caution if skin infection.

Dosing :

0.05% as a cream/ointment/lotion.
<12 years:
Not recommended due to systemic adverse reactions.
>12 years:
Topically used sparingly where required twice daily, maximum dose of 50 g/week. Not to be treated for more than 2 weeks.

Adverse Effect :

Serious reactions: HPA axis suppression, Cushing syndrome, hyperglycemia, intracranial hypertension.

Common Reactions: Stinging, burning, pruritus, secondary infection, dryness, erythema, acneiform dermatitis, skin atrophy, leukoderma, perioral dermatitis, vesiculation, miliaria, rash, folliculitis, hypertrichosis, hypopigmentation allergic contact dermatitis, striae.

Interaction :


Hepatic Dose :

No dosage adjustments are needed.
02/21/2024 01:23:03 Halobetasol Propionate
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