Drug Index

Halobetasol Propionate

 
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Mechanism :

Inhibits multiple inflammatory cytokines; produces multiple glucocorticoid and mineralocorticoid effects.


Indication :

• Inflammatory, pruritic & steroid-responsive dermatoses

• Adjunctive treatment in nodular prurigo

• Chronic discoid lupus erythematosus

• Familial benign pemphigus

• Dyshidrosis

• Mycosis fungoides

• Alopecia areata

• Psoriasis

• Seborrheic dermatitis


Contraindications :

Hypersensitivity to drug/class/component.

Caution if skin infection.


Dosing :

0.05% as a cream/ointment/lotion.

<12 years: Not recommended due to systemic adverse reactions.

>12 years: Topically used sparingly where required twice daily, maximum dose of 50 g/week. Not to be treated for more than 2 weeks.


Adverse Effect :

Serious reactions: HPA axis suppression, Cushing syndrome, hyperglycemia, intracranial hypertension.

Common Reactions: Stinging, burning, pruritus, secondary infection, dryness, erythema, acneiform dermatitis, skin atrophy, leukoderma, perioral dermatitis, vesiculation, miliaria, rash, folliculitis, hypertrichosis, hypopigmentation allergic contact dermatitis, striae.


Interaction :

None.


07/19/2019 03:59:04 Halobetasol Propionate
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