Drug Index

Hyoscine Butyl Bromide

Mechanism :

Hyoscine Butylbromide exhibits mild anticholinergic and spasmolytic atropine-like actions and possesses marked ganglionic blocking and curariform properties. Hyoscine Butylbromide is devoid of central nervous actions. Reduces peristalsis without loss of tone in peptic ulcer therapy; reduces spasm in gastrointestinal, biliary, and renal conditions.

Indication :

  • Abdominal colic
  • Renal colic

Contraindications :

Contraindicated in patients with myasthenia gravis, megacolon, glaucoma and in patients with known hypersensitivity to hyoscine butylbromide.

Dosing :

5-12 years:
10 mg/dose 3-4 times daily.
12-18 years:
20 mg/dose 3-4 times daily.
IM/IV: Max: 1.2 mg/kg/day.
<6 years:
5 mg/dose 3-4 times daily.
6-12 years:
5-10 mg/dose 3-4 times daily.
>12 years:
20 mg/dose 3-4 times daily.

Adverse Effect :

Dry mouth, constipation, tachycardia, visual accommodation disturbances, and urinary retention. Less commonly: rash, itching, swelling of the hands or feet, dizziness, diarrhea, vision problems.

Interaction :

Tricyclic Antidepressants, Antihistamines, Quinidine, Amantadine, Phenothiazines, Butyrophenones and Disopyramide: Increased anticholinergic effects.
Metoclopramide: Con­comitant treatment may decrease effect of both drugs on gastrointestinal tract.
Beta-agonists: Tachycardic ef­fects may be en­hanced.

Renal Dose :

Dose in Renal Impairment GFR (mL/min)
20-50Dose as in normal renal function
10-20Dose as in normal renal function
<10Dose as in normal renal function

Dose in Patients undergoing Renal Replacement Therapies
CAPDDialysed. Dose as in normal renal function
HDDialysed. Dose as in normal renal function
HDF/High fluxDialysed. Dose as in normal renal function
CAV/VVHDNot Dialysed. Dose as in normal renal function
02/17/2021 11:51:21 Hyoscine Butyl Bromide
Disclaimer: The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0