Drug Index

Levocetirizine

 
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Mechanism :

Levocetirizine works by blocking histamine receptors. It does not prevent the actual release of histamine from mast cells, but prevents it binding to its receptors. This in turn prevents the release of other allergy chemicals and increased blood supply to the area and provides relief from the typical symptoms of hay fever.


Indication :

• Seasonal allergic rhinitis

• Perennial allergic rhinitis

• Chronic idiopathic urticaria


Contraindications :

Hypersensitivity to drug/class/component, End Stage Renal Disease, Hemodialysis, Renal impairment (6 mo-11 yo pts).

Caution if renal impairment, CNS depressant use, alcohol use, prostatic hypertrophy, spinal cord injury.


Dosing :

Safety and efficacy not established in children under 6 months of age.

6 months-5 years: 1.25 mg orally in the evening.

6-12 years: 2.5 mg orally in the evening.

>12 years: 2.5-5 mg orally in the evening.


Adverse Effect :

Common Reactions: Somnolence, fatigue, asthenia, urinary retention, nasopharyngitis, xerostomia, fever, diarrhea, vomiting, cough, pharyngitis, otitis media, epistaxis

Serious Reactions: Anaphylaxis, hypersensitivity reaction, seizures.


Interaction :

Avoid/Use Alternative:
Doxylamine
Caution Advised:
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07/19/2019 03:19:22 Levocetirizine
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