Methscopalamine

Mechanism :

It is a quaternary ammonium derivative of scopolamine that exerts anticholinergic effects

Indication :

• Off-label: Peptic Ulcer Disease (adjunctive therapy)

Contraindications :

Hypersensitivity to methscopolamine, any component of the formulation, or related drugs; glaucoma; obstructive uropathy; obstructive disease of the GI tract; paralytic ileus; intestinal atony of elderly or debilitated patients.

Dosing :

Adverse Effect :

Allergic reaction, blurred vision, cycloplegia, mydriasis, headache, dizziness, drowsiness, palpitation, tachycardia, nausea, vomiting, taste loss, urinary retention.

Interaction :

Acetylcholinesterase Inhibitors: May diminish the therapeutic effect of Anticholinergic Agents.
Anticholinergic Agents: May enhance the adverse/toxic effect of other Anticholinergic Agents.
Glucagon: Anticholinergic Agents may enhance the adverse/toxic effect of Glucagon.
Opioid Analgesics: Anticholinergic Agents may enhance the adverse/toxic effect of Opioid Analgesics.
Potassium Chloride: Anticholinergic Agents may enhance the ulcerogenic effect of Potassium Chloride.