Drug Index


Mechanism :

It is a quaternary ammonium derivative of scopolamine that exerts anticholinergic effects

Indication :

  • Off-label: Peptic Ulcer Disease (adjunctive therapy)

Contraindications :

Hypersensitivity to methscopolamine, any component of the formulation, or related drugs; glaucoma; obstructive uropathy; obstructive disease of the GI tract; paralytic ileus; intestinal atony of elderly or debilitated patients.

Dosing :

0.2 mg/kg/day OR 6 mg/m²/day every 8 hours.

Adverse Effect :

Allergic reaction, blurred vision, cycloplegia, mydriasis, headache, dizziness, drowsiness, palpitation, tachycardia, nausea, vomiting, taste loss, urinary retention.

Interaction :

Acetylcholinesterase Inhibitors: May diminish the therapeutic effect of Anticholinergic Agents.
Anticholinergic Agents: May enhance the adverse/toxic effect of other Anticholinergic Agents.
Glucagon: Anticholinergic Agents may enhance the adverse/toxic effect of Glucagon.
Opioid Analgesics: Anticholinergic Agents may enhance the adverse/toxic effect of Opioid Analgesics.
Potassium Chloride: Anticholinergic Agents may enhance the ulcerogenic effect of Potassium Chloride.

01/24/2024 19:16:17 Methscopalamine
Disclaimer: The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0