Drug Index

Mechanism :

Sodium Chloride is source of water and electrolytes. It is capable of inducing diuresis depending on the clinical condition of the patient. It is a crystalloid given intravenously in case of shock, dehydration, and diarrhoea to increase the plasma volume.

Indication :

  • Hyponatremia
  • Shock
  • Maintenance fluids
  • Dehydration

Contraindications :

Contraindicated in any situation where salt retention is undesirable such as edema, heart disease, cardiac decompensation and primary or secondary aldosteronism.

Dosing :

IV. Upto 10 kg:
100 ml/kg/day IV.
10-20 kg:
100 ml/kg/day upto 10 kgs + 50 ml/kg/day above 10 kg.
Above 20 kg:
100 ml/kg/day upto 10 kg + 50 ml/kg/day for 10-20 kg + 20 ml/kg/day above 20 kg.

Adverse Effect :

Infection at the site of injection, thrombophlebitis.

Interaction :

Corticosteroids or Corticotropin: Caution must be exercised in the administration of Sodium Chloride.

Hepatic Dose :

No dosage adjustments are recommended.
09/28/2020 06:32:10 Normal Saline
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