Drug Index


Mechanism :

It is a selective alpha 2 agonist and a nasal decongestant that acts by causing nasal vasoconstriction.

Indication :

  • Nasal congestion

Contraindications :

Use with caution in patients with high blood pressure; arrhythmias; thyroid problems; diabetes; glaucoma.

Dosing :

0.05% solution 2-3 drops in each nostril 12 hourly. Oxymetazoline nasal should not be used for longer than 3 to 5 days. Longer use could cause damage to the nasal tissue and lead to chronic congestion.

Adverse Effect :

Prolonged use may cause atrophic rhinitis and anosmia. It may cause rebound congestion on stopping the drug. Other side effects include, insomnia, headache, burning, stinging, dryness, and sneezing.

Interaction :

Monoamine Oxidase Inhibitor: Should not be used if the patient has taken a monoamine oxidase (MAO) inhibitor such as isocarboxazid, phenelzine, or tranylcypromine in the last 14 days.

Hepatic Dose :

No dose adjustment recommended.
02/14/2024 21:33:08 Oxymetazoline
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