Drug Index

Palivizumab

 
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Mechanism :

Palivizumab is a humanized monoclonal antibody produced by recombinant DNA technology, directed to an epitope in the A antigenic site of the F protein of respiratory syncytial virus.


Indication :

• Respiratory syncytial virus infections in children born at less than 36-week gestation and less than 6 months age at beginning of RSV season

• Bronchopulmonary dysplasia


Contraindications :

Should not be used in pediatric patients with a history of a severe prior reaction to palivizumab or other components of this product. Care should be taken in patients with thrombocytopenia or any coagulation disorders.


Dosing :

15 mg/kg IM once monthly during RSV season, starting just prior to the beginning of the RSV season, for no more than 5 doses.


Adverse Effect :

Antibody formation, anaphylaxis and acute hypersensitivity reactions, cough, wheezing, diarrhea, vomiting, gastroenteritis, rash.


Interaction :

No formal drug-drug interaction studies were conducted.


07/17/2019 11:12:17 Palivizumab
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