Propylhexedrine
Mechanism :
Cycloalkylamine; alpha adrenergic agonist; stimulates alpha-adrenergic receptors in nasal conjunctiva and arterioles to produce vasoconstriction that results in nasal decongestion.
Indication :
Contraindications :
Hypersensitivity to propylhexedrine or any component of the formulation.
Dosing :
6-12 years:
Two inhalations (Each inhalation is 250 mg) in each nostril, not more frequently than every 2 hours for 3 days.
Adverse Effect :
Local nasal burning, stinging, sneezing, increased nasal discharge.
Interaction :
Alpha1-Blockers: May diminish the vasoconstricting effect of Alpha1-Agonists.
Ergot Derivatives: May enhance the hypertensive effect of Alpha1-Agonists.
Monoamine Oxidase Inhibitors: May enhance the hypertensive effect of Alpha1-Agonists.
Tricyclic Antidepressants: May enhance the vasopressor effect of Alpha1-Agonists.
Hepatic Dose :
No dosage adjustments are recommended.