Drug Index

Retapamulin

 
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Mechanism :

Primarily bacteriostatic; inhibits normal bacterial protein biosynthesis by binding at a unique site (protein L3) on the ribosomal 50S subunit.


Indication :

• Treatment of impetigo due to Staphylococcus aureus (methicillin-susceptible isolates only)

• Streptococcus pyogenes in pediatric patients 9 months and older.


Contraindications :

No contraindications.


Dosing :

Apply a thin layer of ointment (1%) to affected area twice daily for 5 days; Maximum: Total treatment area should not exceed 2% of total body surface area.


Adverse Effect :

Headache, eczema, diarrhea, nausea, application site irritation, nasopharyngitis.


Interaction :

CYP3A4 Inhibitors: May increase the serum concentration of Retapamulin.


07/18/2019 02:15:53 Retapamulin
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