Drug Index


Mechanism :

Primarily bacteriostatic; inhibits normal bacterial protein biosynthesis by binding at a unique site (protein L3) on the ribosomal 50S subunit.

Indication :

  • Treatment of impetigo due to Staphylococcus aureus (methicillin-susceptible isolates only)
  • Streptococcus pyogenes in pediatric patients 9 months and older.

Contraindications :

No contraindications.

Dosing :

Apply a thin layer of ointment (1%) to affected area twice daily for 5 days;
Total treatment area should not exceed 2% of total body surface area.

Adverse Effect :

Headache, eczema, diarrhea, nausea, application site irritation, nasopharyngitis.

Interaction :

CYP3A4 Inhibitors: May increase the serum concentration of Retapamulin.

Hepatic Dose :

No dose adjustment recommended.
03/23/2024 05:38:17 Retapamulin
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