Drug Index


Mechanism :

Although the exact mechanism of tazarotene action is not known, studies have shown that the active form of the drug (tazarotenic acid) binds to all three members of the retinoic acid receptor (RAR) family: RARA, RARB, and RARG, but shows relative selectivity for RARB, and RARG and may modify gene expression. It also has affinity for RXR receptors.

Indication :

  • Used to treat psoriasis, acne and sun damaged skin (photodamage)

Contraindications :

Allergic to any ingredient in tazarotene cream.

Pregnant or able to become pregnant and are not using effective birth control.

Dosing :

Available astopical cream 0.1% gel 0.1%.
12 years or older:
Apply a thin layer (2 mg/cm²) once a day, in the evening.

Adverse Effect :

Burning or stinging of the skin, changes in color of the treated skin, desquamation, erythema, deep grooves or lines in the skin, dryness, itching, peeling, or redness of the skin.

Interaction :

Searched, but no interactions found.

Hepatic Dose :

No dose adjustment recommended.
03/13/2024 04:38:03 Tazarotene
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