Drug Index

Simethicone

 
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Mechanism :

Simethicone is an anti-flatulence agent that acts by defoaming the gastric juice and thus, prevents the gas formation. It is used to treat post-operative gastrointestinal disorders, peptic ulcer and irritable bowel syndrome.


Indication :

• Flatulence


Contraindications :

Hypersensitivity to simethicone.


Dosing :

Give PO every 6 hours after meals and at bedtime.

<2 years: 20 mg/dose; do not exceed 240 mg/day.

2-12 years: 40 mg/dose; do not exceed 480 mg/day.

>12 years: 40-125 mg/dose; not to exceed 500 mg/day.


Adverse Effect :

Dysphagia, melena, diarrhea, nausea, vomiting, abdominal pain, headache, eructation.


Interaction :

No significant interactions found.


07/18/2019 12:34:06 Simethicone
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