Drug Index


Mechanism :

It is a naturally occurring coagulant, usually used in conditions associated with bleeding, to stop bleeding. It is applied topically for minor bleeds.

Indication :

  • Control of hemorrhage

Contraindications :

Hypersensitivity to product or any component.

Dosing :

May soak in up to 10 mL of absorbable gelatin sponge and then applied on bleeding surface. Do not inject systemically, can lead to intravascular clotting and death.
Severe bleeding:
Concentrations of 1000-2000 units/mL.
Mild/moderate bleeding:
Concentrations of 100 units/mL.

Adverse Effect :

Skin incision pain, nausea with vomiting, immune hypersensitivity reaction, thromboembolic disorder, antibody formation.

Hepatic Dose :

No data available
02/14/2024 19:55:13 Thrombin
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