Drug Index

Thrombin

 
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Mechanism :

It is a naturally occurring coagulant, usually used in conditions associated with bleeding, to stop bleeding. It is applied topically for minor bleeds.


Indication :

• Control of hemorrhage


Contraindications :

Hypersensitivity to product or any component.


Dosing :

May soak in up to 10 mL of absorbable gelatin sponge and then applied on bleeding surface. Do not inject systemically, can lead to intravascular clotting and death.

Severe bleeding: Concentrations of 1000-2000 units/mL.

Mild/moderate bleeding: Concentrations of 100 units/mL.


Adverse Effect :

Skin incision pain, nausea with vomiting, immune hypersensitivity reaction, thromboembolic disorder, antibody formation.

07/15/2019 05:38:40 Thrombin
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