Drug Index

Xylometazoline

Mechanism :

Xylometazoline is a sympathomimetic drug used to relieve nasal congestion.


Indication :

  • Allergic rhinitis
  • Common cold
  • Sinusitis

Contraindications :

Contraindicated in hypersensitivity to any ingredient, trans-sphenoidal hypophysectomy, and in infants <3 months of age.


Dosing :

Intranasal: 12-18 years: 0.05% spray. 2-3 sprays per nostril every 8-10 hours.
Max: 3 doses a day.

Adverse Effect :

Rarely, rebound congestion, mild tingling, burning sensation in the nose or throat, local irritation or dryness of the nasal mucosa. Intranasal use of xylometazoline may occasionally cause systemic sympathomimetic effects such as hypertension, nervousness, nausea, dizziness, headache, anxiety, tremor, insomnia, palpitation, tachycardia and arrhythmia. In isolated cases, systemic allergic reactions or transient visual disturbances have been reported


Interaction :

Isocarboxazid, Linezolid, Phenelzine, Selegiline Transdermal, Tranylcypromine: Increases the effect of xylometazoline by pharmacodynamic synergism.



Hepatic Dose :

No dosage adjustments are recommended.
01/15/2021 10:34:37 Xylometazoline
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