ISSN - 0973-0958

Pediatric Oncall Journal View Article

Congenital Candidiasis
Shrabani Mandal, Mukut Banerjee, Asim Kumar Mallick.
Department of Pediatrics, NRS Medical College and Hospital, Kolkata, India.
Congenital candidiasis is an extremely rare disease with less than 100 cases being reported in the literature. It presents within six days of life with manifestations ranging from localized skin disease to systemic involvement in the form of respiratory distress, sepsis with hepatosplenomegaly, and death. Intrauterine infection by candida may give rise to this condition and it differs from neonatal candidiasis, which manifests as thrush or diaper dermatitis. We report a neonate who presented with diffuse pustular eruption on erythematous background involving head, face, trunk, and palms at birth. Candida albicans was identified on blood culture and budding yeast cells were seen on 10% potassium hydroxide (KOH) preparation on the pus drained from the pustules. Intravenous fluconazole and topical ketoconazole were given and the condition improved completely in two weeks.

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