Menu
Disease
A-Z
Health Topics
Alternative Medicine
Developmental Pediatrics
General Pediatrics
Genetics
Immunodeficiencies
Infectious Diseases
Laboratory Medicine
Neonatology
Nutrition
Pediatric Cardiology
View all Topics
Featured Articles
Circumcision
Anal itching
Anal fissure
Diabetic ketoacidosis
Skin allergies
Hypospadias
Kids Corner
Health and Knowledge with fun.
Drugs &
Calculators
Medical Calculators
Drug Calculators
Growth Calculators
Renal Calculators
View all Calcualtors
Drug Index
ACE inhibitor
Alkylating agents
Allergies
View all Drugs
Poisoning Center
Aluminum phosphide
Anti-histaminics
Antidepressants
View all Drugs
Medical Eqipments
Monitors
Pumps
Incubators
View all Equipments
Diagnostic Aid
Get your diffrential
diagnosis.
Consult
& Posts
Ask a Doctor
Diagnostic Dilemma
Question of the Week
Pediatric Blogs
Spot Diagnosis
Grand Rounds
Pedi Poll
Pediatric
Journal
Current Issue
All Issues
Advance Access
About the Journal
Submit Article
Books
& Apps
Book Store
Pediatric Oncall
Medical Calculators
Vaccine Reminder
Pediatric Oncall Journal
Drug Center
Parenting
CME &
Videos
Upcoming Conferences
Conference Abstracts
MCQs
Videos
Vaccine
Reminder
Sign In
Pediatric Oncall Journal
Home
Articles & Issues
Current Issue
All Issues
Advance Access
About
Pediatric Oncall Journal
Editorial Board
Peer Review Policy
Other Policies
Copyrights
Privacy Statement
Contribute
Open Access Statement
Authorship & Acknowledgment
Author Guidelines
Forms
Submit Manuscript
Cord blood Thyroid Stimulating Hormone Level - and the influence of perinatal and other factors on it
Abstract
Full Text
PDF
Volume
16
, Issue
3
July-September 2019
Pages: 79-82
ARTICLE HISTORY
Received 20 November 2018
Accepted 20 May 2019
DOI:
https://doi.org/10.7199/ped.oncall.2019.31
CITE THIS ARTICLE
Poyekar S, Pratinidhi S, Prasad S S, Sardar Z S, Kankariya B, Bhole O. Cord blood Thyroid Stimulating Hormone Level - and the influence of perinatal and other factors on it. Pediatr Oncall J. 2019;16: 79-82. doi: 10.7199/ped.oncall.2019.31
Journal Subscription
Pediatric Oncall Journal
Subscribe Now
ORIGINAL ARTICLE
Cord blood Thyroid Stimulating Hormone Level - and the influence of perinatal and other factors on it
Subhash Poyekar
1
, Shilpa Pratinidhi
2
, Swapnil S Prasad
3
, Zainab S Sardar
3
, Bhavesh Kankariya
3
, Om Bhole
3
.
1
Department of Paediatrics, Rural Medical College, Loni, Maharashtra, India,
2
Department of Biochemistry, MIMER Medical College, Talegaon-Dabhade, Maharashtra, India,
3
MIMER Medical College, Talegaon-Dabhade, Maharashtra, India.
Show affiliations
Abstract
Background:
Thyroid hormone is essential for growth and development especially the brain. Deficiency of thyroid hormone i.e. congenital hypothyroidism (CH) is the commonest cause of preventable mental retardation. As it is difficult to diagnose CH with clinical symptoms at birth, most patients with CH are diagnosed by laboratory results. Early detection is important, either by Thyroid Stimulating Hormone (TSH) or T4 estimation or both by newborn screening. Cord blood TSH (CB-TSH) estimation has high sensitivity, but various maternal and perinatal factors affect the CB-TSH levels, which may interfere with the interpretation.
Aim:
This study was done to find out the various maternal and perinatal factors affecting CB-TSH level.
Materials and Methods:
A hospital-based cross-sectional study was conducted in the Department of Paediatrics, Obstetrics and Biochemistry of Medical College, Pune over a period of one and half year. Cord blood TSH level was estimated and the results were statistically analysed with respect to various maternal and perinatal factors. A TSH cut-off of >20 µIU/mL was considered as high.
Result:
A total number of 726 newborns were enrolled in the study. The mean CB-TSH was 8.9 µIU/mL with 54 (7.5%) newborns having values more than 20 µIU/mL. CB-TSH was significantly raised in male babies, in first order neonates delivered by vaginal delivery. Neonates who had fetal distress or non-progress of labour had significantly higher CB-TSH than those who were delivered by elective caesarean section. Gestational age and birth weight of newborns did not have influence on CB-TSH.
Conclusion:
About 7.5% newborns had elevated CB-TSH levels. Gender of the baby, perinatal stress factors and mode of delivery have significant relationship with the CB-TSH level. Hence, due consideration should be given to these factors while interpreting CB-TSH levels.
READ FULL TEXT
This work is licensed under a
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License
Disclaimer: The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.
X
Sign In
Disease A-Z
Health Topics
Alternative Medicine
Developmental Pediatrics
General Pediatrics
Genetics
Immunodeficiencies
Infectious Diseases
Laboratory Medicine
Neonatology
Nutrition
Pediatric Cardiology
View all topics
Featured Articles
Circumcision
Anal itching
Anal fissure
Diabetic ketoacidosis
Skin allergies
Hypospadias
Kids Corner
Drugs & Calculators
Medical Calculators
Drug Calculators
Growth Calculators
Renal Calculators
View all Calculators
Drug Index
ACE inhibitor
Alkylating agents
Allergies
View all Drugs
Poisoning Center
Aluminum phosphide
Anti-histaminics
Antidepressants
View all Drugs
Medical Eqipments
Monitors
Pumps
Incubators
View all Eqipments
Diagnostic Aid
Consult & Posts
Ask a Doctor
Diagnostic Dilemma
Question of the Week
Pediatric Blogs
Spot Diagnosis
Grand Rounds
Pedi Poll
Pediatric Oncall Journal
Current Issue
All Issues
Advance Access
About the Journal
Submit Article
Books & Apps
Book Store
Pediatric Oncall
Medical Calculators
Vaccine Reminder
Pediatric Oncall Journal
Drug Center
Parenting
CME & Videos
Upcoming Conferences
Conference Abstracts
MCQs
Videos
Vaccine Reminder
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0