ISSN - 0973-0958

Pediatric Oncall Journal View Article

Prevalence and Profile of Vitamin D in Infants
Rachana Gedam Wagmare1, Drishti Tolani2.
1Consultant Pediatrician, Natalee Clinic, Pune, India,
2Seth G S Medical College, Seth G S Medical College, KEM Hospital, Mumbai, India.
Abstract
Aim: To determine the prevalence and profile of vitamin D in infants
Methods: This cross-sectional analysis was done over a period of 6 months in 29 infants admitted in our pediatric ward at a tertiary referral hospital. Their serum 25 hydroxyvitamin D, calcium, phosphorous, alkaline phosphatase and hemoglobin levels were noted. Association of vitamin D levels with various clinical and laboratory markers were analyzed.
Results: Mean age of presentation was 6.1±3 months. Male to female ratio was 15:14. Mean serum calcium was 9.2 ± 1.7 mg/dl, alkaline phosphatase was 501.6±427.3 IU/ml and phosphorus was 5.1 ± 1.4 and mean serum vitamin D levels were 15.7 ± 10.9 ng/ml. Vitamin D was deficient in 10 (34.5%) patients and insufficient in 11 patients (37.9%). Lower respiratory tract infection (LRTI) was present in 17 (58.6%) patients, hypocalcemic seizures were present in 7 (20.7%), anemia was seen in 25 (86.2%) and 16 (55.2%) patients were malnourished. Gender (p=0.46), anemia (p=0.608), malnutrition (p=0.184), LRTI (p=0.514), hypocalcemia (p=0.0.7), elevated alkaline phosphatase (p=0.11) had no association with vitamin D levels whereas low serum phosphorous levels (p=0.031) was more common in those with insufficient vitamin D levels and seizures were common in those with vitamin D deficiency.
Conclusion: Vitamin D insufficiency and deficiency is highly prevalent in infants less than 1 year of age. Low serum phosphorus is seen in vitamin D insufficiency. Seizures occur in patients with vitamin D deficiency.

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