ISSN - 0973-0958
   
 
Levels of Vitamin D in Patients of Childhood Asthma
Avinash Kumar, Ratan Gupta, P K Debata, Dinesh K Taneja, K C Aggarwal.
Department of Pediatrics, Vardhman Mahavir Medical College and Safdarjang Hospital, New Delhi.
 
Abstract

Background: Lack of vitamin D has been linked to increased incidence of asthma in children. In this study we tried to find out the relation of vitamin D status in childhood asthma.
Methods: Hospital based analytical case control study. Vitamin D level was assessed in both cases and controls and its association with asthma was assessed in the age group 5- 12 years.
Results: Median serum 25 (OH) D was very low among cases 15.0 (IQR: 10•0, 19•5) as compared to controls 20•5 (IQR: 15•5, 28•0) and this difference was highly significant (p<0•001). However, Vitamin D deficiency was also found to be prevalent in our control population, with 47.6% having low serum Vitamin D levels. With multivariate analysis no relation was found between Vitamin D and the allergic markers [IgE & eosinophil count]. There was a significant relation between the low level of Vitamin D and the severity of asthma (p<0•001). The mean value of calcium was low and alkaline phosphatase and phosphate were higher in cases than the control group.
Conclusion: Though the causality of childhood asthma due to Vitamin D deficiency is not established, low Vitamin D is an aggravating factor for childhood asthma. Therefore, Vitamin D supplementation may be considered as an adjuvant therapy in asthmatic children.
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License
Disclaimer: The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0