Non – Steroidal Anti – Inflammatory Drugs

Poisning Center › Agricultural-poisons › Non – steroidal anti – inflammatory drugs

Non – steroidal anti – inflammatory drugs

Fatal Dose :
10 to 20gm or more
Fatal Period :
Ingestion and inhalation
Mechanism of action :
most of these drugs act by inhibiting prostaglandin synthesis
Clinical Picture :
• GIT: Nausea, vomiting, epigastric pain, peptic ulceration • CNS: drowsiness, lethargy, confusion, vertigo • CVS: hypotension, aplastic anemia • RS: cyanosis • Renal: nephritis
Treatment :
• gastric lavage • hemoperfusion • symptomatic

Antidepressants Aspirin (acetyl salicylic acid)

Hallucinogens Insulin

Formaldehyde Nitrates and nitrites

Paracetamol (acetaminophen) Stimulants

Anti-histaminics Barbiturates

Benzodiazapines

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