Flourides
 
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Sodium fluoride is used in rat poisons and cockroach powders. Sodium silicflouride, flouroacetamide and flouroacetate are used as rodenticides.
Route :
Ingestion
Fatal Dose :
5mg/kg body weight
Mechanism of action :
•Flouride compounds react with acid in the stomach and form hydrofluoric acid which is corrosive. •They also cause hypocalcemia, hypomagnesia and hypokalemia •Acts as a general protoplasmic poison
Clinical Picture :
•Ingestion causes burning, pain in mouth and epigastrium, thirst, salivation, vomiting, diarrhea, haematemesis and hematuria •Coma and convulsions
Treatment :
•Calcium orally and i.v. •Stomach wash with lime water or milk
07/14/2019 01:50:58 Flourides
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