D.d.T. (dichloro – Diphenyl – Trichloroethane) - Poisoning Center

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Poisning Center › Neurotoxic-poisons › D.d.t. (dichloro – diphenyl – trichloroethane)

D.d.t. (dichloro – diphenyl – trichloroethane)

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It is a white crystalline solid. It is insoluble in water but soluble in alcohol and kerosene oil. it is used as 2-5 percent solutionin kerosene to kill bugs, mosquitoes, lice, fleas and flies
Route :
Ingestion , inhalation, absorbed through skin
Fatal Dose :
30gm
Fatal Period :
24hrs
Mechanism of action :
It interferes with nerve impulse transmission. CNS is first stimulated and then depressed
Clinical Picture :
• Acute poisoning manifests as: vomiting, cough, excitation, vomiting, tremors, convulsions,incoordination, paralysis of muscles, pulmonasry edema and coma • In chronic poisoning: mental anxiety, insomnia, muscular weakness and pain, anemia, convulsions, coma
Treatment :
• Gastric lavage • I.V. calcium gluconate • Injection atropine • Symptomatic

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