Endrin
 
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It is insoluble in water but soluble in alcohol and kerosene oil. it is bitter to taste. it is commonly used as sprays or dusts diluted with inert clays
Route :
Ingestion
Fatal Dose :
5 to 6gm
Fatal Period :
1 to several hours
Mechanism of action :
It interferes with nerve impulse transmission. CNS is first stimulated and then depressed
Clinical Picture :
• Salivation, nausea , vomiting, abdominal pain • Hoarseness of voice, coughing, froth at mouth and nose, dyspnoea • Headache, giddiness, restlessness, hyperirritabilty, dilated pupils, in-cordination, mental confusion, tremors, convulsions • In non-fatal cases, patient feels well after 24hrs
Treatment :
• Clothing should be removed and skin washed with soap and water • Gastric lavage • Animal charcoal • Cholestyramine : increased the fecal excretionof endrin • Symptomatic
07/14/2019 01:55:09 Endrin
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