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Poisning Center › Neurotoxic-poisons › Fuels ( kerosene, petrol and naphthalene)
Fuels ( kerosene, petrol and naphthalene)
 
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All important fuels are hydrocarbons derived from petroleum
Route :
Ingestion, chronic inhalation
Fatal Dose :
kerosene – 15 to 30ml, petrol – 10 ml
Fatal Period :
few hours
Mechanism of action :
• They depress CNS and act as irritants, because they dissolve fat • The effect on liver, kidney and bone marrow may be due to contaminants as benzene. Benzene is a human carcinogen
Clinical Picture :
• Kerosene taste and smell • Chronic contact with skin causes eczematoid dermatitis with redness and inflammattion • Burning in upper GIT • Nausea, vomiting, colicky pain and diarrhea • Respiration slow and shallow, cyanosis, bronchopneumonia and pulmonary edema • Photophobia, redness in eyes • CNS depression and convulsions and coma • Pupils initially constricted and finally dilated
Treatment :
• Stomach wash with warm water or sodium bicarbonate • 250 ml liquid paraffin orally – dissolves kerosene and slows its absorption, followed by saline cathartic • If inhaled- oxygenation and artificial respiration • Symptomatic
05/20/2020 23:19:26 Fuels ( kerosene, petrol and naphthalene)
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