Hydrocyanic acid (prussic acid or cyanogen
 
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Hydrocyanic acid is a vegetable acid found in many fruits and leaves such as almond, apricot, apple, cheery, peach, plum, pear, and in certain oils and besns where it exists as a glucoside amygdalin. The pure acid is colorless, transparent volatile liquid with an odor like bitter almonds and is rapidly decomposed by exposure to light
Route :
Inhalation, ingestion, ingestion through skin
Fatal Dose :
50 to 60mg of pure acid, 200 to 300mg of sodium or potassium cyanide
Fatal Period :
2 to 10 minutes
Mechanism of action :
•Cyanide inhibits the action of various enzymes of various enzymes. • Cyanides act by reducing the oxygen carrying capacity of blood. •There is interference with with intracellular oxidative process in tissues
Clinical Picture :
This is the most rapid of all poisons. •CNS: headache, vertigo, perspiration, anxiety, convulsions, paralysis •GIT: bitter, acid, burning taste, constriction or numbness of throat •RS: odor of bitter almonds in breath. Initially tachypnoea and dyspnoea. Later rapid slowing of respiratory rate with severe respiratory depression and cyanosis •CVS: Initially hypertension, later tachycardia with hypotension •Glassy and prominent eyes with dilated pupils, unreactive
Treatment :
•Treatment should be started immediately •The principle of treatment is to reverse the cyanide – cytochrome combination.
07/14/2019 01:38:25 Hydrocyanic acid (prussic acid or cyanogen
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