HEPATOBLASTOMA

 
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Question
An 8 months old boy was diagnosed as hepatoblastoma at 4 months of age for which he underwent chemotherapy {4 cycles of PLADO regimen} and subsequently underwent right sided extensive hepatic resection at 8 months of age. Pre-operatively his LFT are shown in Table 1. Post operatively, in 24 hours, his LFT are depicted in Table 1 which shows marked elevation of liver transaminases with jaundice. He continued to have hemorrhagic ascitis though ascitic fluid cytospin was negative for malignant cells. He did have prolonged inferior vena clamping during intra operative period. He subsequently died after 6 days post operative.
Expert Opinion :
It may be due to prolonged clamping of IVC and hepatic ischemia.
Answer Discussion :
H
habib jawaid
bubble
prolonged clamping ALT,AST very high equals Hepatic ischemia
4 years ago
D
DrSusanJohn Mathews
bubble
may be ischemia of liver
4 years ago

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EAP 2017
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