NEONATAL HEPATITIS WITH MOTHER HBsAg positive

Question

Home | All Discussions | Submit Dilemma

NEONATAL HEPATITIS WITH MOTHER HBsAg positive

Author: Pediatric Oncall

Question
A one month old boy born of non consanguineous marriage presented with jaundice without clay coloured stools for 3 days. Mother was a chronic carrier of Hepatitis B and had jaundice at 18 years of age. There were no antenatal or post natal complications. On examination, height was 42 cms, weight was 1.75 kg. There was jaundice and hepatomegaly. Others systems were normal. Investigations showed:
• Hemoglobin = 9.5 gm, dl
• WBC = 18,000, cumm
• Platelets = 3,75,000, cumm
• Bilirubin = 15.2 mg, dl {direct bilirubin = 3.2 mg, dl}, SGOT = 106 IU, L, SGPT = 44 IU, L, Total proteins = 7 gm, dl, Albumin = 4.3 gm, dl, Alkaline phosphatase = 293 IU, L.
• PT and PTT = deranged
• TORCH = CMV, Rubella IgG positive
• HIV, Hepatitis C antibody = Negative
• Ophthalmological examination, Hearing test = Negative
• USG Abdomen = Gall bladder seen
• Urine reducing substance = Negative
• Echocardiography = Normal

The baby was given Hepatitis B Vaccine and Hepatitis B Immunoglobulin within 72 hours of birth.

Is this neonatal hepatitis due to Hepatitis B _?

Answer Discussion :

C

Cesar Antonio Ortega

0

This presentation is most consistant with congenital Rubella given IUGR.

11 years ago

B

bela

0

Hepatitis b infection

11 years ago

View More Comments

Answer 1

This child`s neonatal cholestasis resolved on its own. His HBsAg at 6 months of age was negative. Thus Hepatitis B was not the cause of neonatal cholestasis.

NEONATAL HEPATITIS WITH MOTHER HBsAg positive

Home

Partner Sites