Drug Index

Benzalkonium Chloride

 
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Mechanism :

Benzalkonium chloride is a quaternary ammonium antiseptic and disinfectant. It is also used as an antimicrobial preservative for pharmaceutical products. It is also used for the disinfection of rigid contact lenses.


Indication :

• Antiseptic and disinfectant


Contraindications :

Incompatible with soaps and other anionic surfactants, citrates, iodides, nitrates, permanganates, salicylates, silver salts, tartrates, and zinc oxide and sulfate.


Dosing :

Topical application

Tincture of benzalkonium chloride 1: 750 is used for the preoperative disinfection of unbroken skin or treatment of superficial injuries.

For preoperative disinfection of mucous membranes and denuded skin, benzalkonium chloride solution in concentrations of 1: 10,000 to 1: 2,000 is used.

For irrigation of the eye, a solution of 1: 10,000 to 1: 5,000 is used.

For urinary bladder and urethral irrigation, a solution 1: 5,000 to 1: 20,000 is used.

For vaginal douche and irrigation, benzalkonium chloride solution 1: 5,000 to 1: 20,000.


Adverse Effect :

Repeated application may cause hypersensitivity reactions. May cause nausea and vomiting if ingested.


Interaction :

Disinfectants containing quaternary ammonium salts should not be used for skin preparation before injections of viscoelastic solutions. Hyaluronic acid will precipitate in the presence of these salts.


07/18/2019 01:51:12 Benzalkonium Chloride
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