Drug Index

Deferiprone

 
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Mechanism :

Deferiprone is an oral drug that chelates iron and is used to treat thalassaemia major.


Indication :

• Iron overload

• Hemolytic anemia on multiple transfusion

• Thalassemia major


Contraindications :

Contraindicated if there is a history of agranulocytosis or recurrent episodes of neutropenia.


Dosing :

Oral

>6 years: 25 mg/kg/dose or 250 mg dose 3 times daily. Max: 100 mg/kg/day.


Adverse Effect :

Nausea, vomiting, altered taste, abdominal pain, increased appetite, reddish/brown urine, joint pain, agranulocytosis, neutropenia, arthropathy.


Interaction :

Neutropenic Drugs: Patients should not take any other neutropenic drugs.


08/11/2019 20:55:03 Deferiprone
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