Drug Index

Glucagon

 
print

Mechanism :

It is a hormone, which is also normally secreted in the body by the pancreas. It stimulates the conversion of glycogen to glucose and gluconeogenesis. Glucagon increases blood glucose concentration and is used in the treatment of hypoglycemia. Glucagon acts only on liver glycogen, converting it to glucose. Glucagon administered through a parenteral route relaxes smooth muscle of the stomach, duodenum, small bowel, and colon.


Indication :

• Hypoglycemia

• Growth hormone testing


Contraindications :

Glucagon is contraindicated in patients with known hypersensitivity to it or in patients with known pheochromocytoma.


Dosing :

Hypoglycemia:

Under 6 years: 0.5 mg SC/IM/IV; repeat after 15 minutes if needed.

Above 6 years: 1 mg SC/IM/IV; repeat after 15 minutes if needed.

Under 25 kg: 500 mcg; repeat after 15 minutes if needed.

>25 kg: 1 mg; repeat after 15 minutes if needed.

GH testing:

>1 month: 100 mcg/kg. Maximum: 1 mg.


Adverse Effect :

Nausea, vomiting, diarrhea, rash, hypotension, tachycardia, hypokalemia, hypersensitivity reactions, necrolytic migratory erythema.


Interaction :

Not significant.


07/17/2019 10:58:19 Glucagon
ask a doctor
Ask a Doctor
Disclaimer: The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0