Drug Index

Bisacodyl

 
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Mechanism :

Bisacodyl is a stimulant laxative. Bisacodyl stimulates the smooth muscle of the intestines. This causes the normal peristalsis. It increases water in the intestines, resulting in a bowel movement.


Indication :

• Laxative

• Bowel cleansing


Contraindications :

In intestinal obstruction and in case of any undiagnosed acute or persistent abdominal symptoms.


Dosing :

6-12 years: 5 mg or 0.3 mg/kg PO at bedtime or before breakfast.

>12 years: 5-15 mg orally at bedtime.


Adverse Effect :

Griping, excessive diarrhea, nausea, vertigo, vomiting. Prolonged use may lead to an atonic non-functioning colon and hyperkalemia.


Interaction :

Antacids: Should not be given within 1 hour of administering bisacodyl.



Renal Dose :

Dose in Renal Impairment GFR (mL/min)
20-50Dose as in normal renal function
10-20Dose as in normal renal function
<10Dose as in normal renal function

Dose in Patients undergoing Renal Replacement Therapies
CAPDUnlikely to be dialysed. Dose as in normal renal function
HDUnlikely to be dialysed. Dose as in normal renal function
HDF/High fluxUnlikely to be dialysed. Dose as in normal renal function
CAV/VVHDUnlikely to be dialysed. Dose as in normal renal function

Hepatic Dose :

No dosage adjustments are recommended.
07/28/2020 02:33:04 Bisacodyl
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