Drug Index

Docusate

 
print

Mechanism :

Docusate is a stool softener. It is used to treat constipation due to hard stools, in painful anorectal conditions such as hemorrhoids. The effect of docusate may not necessarily be all due to its surfactant properties. Perfusion studies suggest that docusates inhibit fluid absorption or stimulate secretion in jejunum.


Indication :

• Painful anorectal conditions

• Constipation (acts as a stool softener)


Contraindications :

Presence of abdominal pain, nausea or vomiting are contraindications.


Dosing :

Oral: Divide in 1-4 doses

<3 years: 10 to 40 mg daily.

3 to 6 years: 20 to 60 mg daily.

6 to 12 years: 40 to 150 mg daily.

>12 years: 50 to 400 mg daily.

Rectal:3 to 18 years: 50 to 100 mg added to a retention or flushing enema once a day. As an enema: 200 to 283 mg once daily.


Adverse Effect :

Cramping, bitter taste, throat irritation, congestion of the rectal mucosa may occur following rectal use, intestinal obstruction.


Interaction :

Mineral oil: Increased absorption of the oil may result. Do not use in the presence of abdominal pain, nausea, fever or vomiting. Frequent or prolonged use may result in dependence on laxatives. Do not administer docusate within 2 hours of another medicine, to avoid reduction of its effect.


08/06/2019 12:18:57 Docusate
ask a doctor
Ask a Doctor
Disclaimer: The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0